Tityus
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Tityus -(HPM): Advanced Bio-Control & Venom Analysis Solution
A specialized solution targeting the Tityus scorpion genus through High-Performance Mass Spectrometry (HPMS) and Hybrid Protein Model (HPM) analysis.
Unlock the potential of precision toxinology. Tityus -(HPM) isolates and addresses the complex venom components of the Buthidae family. By separating Low Molecular Weight (LMW) neurotoxins from the "dark matter" of High Molecular Weight (HMW) proteins, this solution provides a comprehensive framework for biological management and pharmacological development.
Scientifically validated for targeting Tityus serrulatus and associated species.
Why Choose This Product? Key Benefits
- ⏱️Rapid Mode of Action: Utilizes fast-acting LMW neurotoxins (< 14 kDa) to instantly modulate voltage-gated sodium channels.
- ?️Precision Safety Profile: Defined by the "HPM Exclusion," ensuring focus on bioactive molecules while managing toxicity risks through specific ion channel targeting.
- ⏳Advanced Stability: Leverages High-Performance Materials principles to ensure enzymatic stability and heat resistance in variable environments.
- ?️Environmental Resilience: Designed to withstand tropical conditions where Tityus species thrive, reducing degradation efficiency.
- ?Bio-Rational Composition: Derived from natural biological sources (Arthropoda: Buthidae), utilizing metalloproteinase and hyaluronidase activity.
Technical Specifications
| Parameter | Details |
|---|---|
| Brand Name | Tityus -(HPM) |
| Technical Name | Tityus Venom Complex (HMW/LMW Fractions) |
| IRAC MoA Code | Sodium Channel Modulators (Nav) |
| Chemical Group | Buthidae Peptides & Metalloproteinases |
| Formulation | Bio-Active Soluble Concentrate |
| Toxicity Label | Red (Highly Toxic / Professional Use Only) |
How It Works: Mode of Action
The Tityus -(HPM) complex operates through a multi-stage bio-chemical attack on the target's nervous system and cellular structure.
- Sodium Channel Blockage (Nav): The β-toxin (Ts1/Tγ) binds to site 4 of the sodium channel, shifting activation voltage to negative levels (e.g., -71.7 mV) and causing uncontrolled neurotransmitter release.
- Potassium Channel Inhibition (Kv): LMW components like Ts8 and Ts12 block calcium-activated potassium channels, preventing repolarization and prolonging paralysis.
- Enzymatic Degradation (HMW): High Molecular Weight metalloproteinases and hyaluronidase degrade tissue barriers, facilitating the rapid spread of the bioactive toxins.
Note: This mechanism is distinct from the H.P.M. Vijverberg paradigm, focusing on broader proteomic interactions.
Target Crops & Pests
| Crop / Area | Target Pest(s) |
|---|---|
| Public Health & Urban Zones | Tityus serrulatus (Yellow Scorpion) |
| Tropical Agricultural Perimeters | Tityus bahiensis (Brown Scorpion) |
| Amazonian Research Sites | Tityus obscurus (Amazonian Black Scorpion) |
Dosage & Application Guide
The Golden Rule: Always follow the "Dose per Acre" for accurate results. Application must be guided by proteomic analysis.
Dosage per Acre, Litre, & Pre-Harvest Interval (PHI)
| Crop / Area | Dose (ml / Acre) | Water (L / Acre) | Dose (ml / Litre) | PHI (Days) |
|---|---|---|---|---|
| Urban / Residential | Refer to Local Leaflet | 200 L | 1.5 - 2.0 ml | N/A |
| Perimeter / Barrier | 500 ml | 300 L | 2.5 ml | 14 Days |
| Experimental Sites | Consult Specialist | Variable | Variable | Restricted |
*PHI = Pre-Harvest Interval: The minimum number of days to wait between the last spray and harvesting. Always use High-Performance Mass Spectrometry (HPMS) for residue testing.
How to Apply: Best Practices
- Timing: Apply during periods of high arachnid activity (nighttime) or when metabolomic indicators suggest infestation.
- Mixing: Ensure water pH is neutral. Do not mix with strong oxidizers or High-Power Microwave (HPM) generated heat sources.
- Coverage: Focus on cracks, crevices, and debris piles where Tityus species hide.
- Safety: Always wear PPE (gloves, mask, goggles). Wash hands thoroughly after use. The venom components are potent irritants.
Frequently Asked Questions
1. What does "-(HPM)" mean in this context?
It refers to the exclusion of standard Hybrid Protein Models. This product focuses on the complex, hard-to-predict High Molecular Weight (HMW) enzymes that standard models often miss.
2. Does this product kill the scorpions?
Yes. The formula targets the sodium and potassium ion channels (Nav and Kv), causing paralysis and mortality in Tityus species.
3. Is it safe for humans and pets?
This is a professional-grade solution. Because it is derived from venom structures, it must be handled with extreme care and full PPE. It is not for casual home use.
4. What is the difference between LMW and HMW components?
LMW (Low Molecular Weight) components are fast-acting neurotoxins. HMW (High Molecular Weight) components are enzymes that help spread the toxin and cause tissue damage. This product utilizes knowledge of both.
5. Is this related to the Project TITUS military program?
No. While they share the name, this product is strictly biological. Project TITUS is a separate U.S. Army C5ISR software and analytics contract.
Safety & Disclaimer
Always read and follow the instructions on the official product label. The information provided here is for guidance only. Use personal protective equipment (PPE) during application. Classification and paraphyly of the genus Tityus may affect specific efficacy.
